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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TRIP6
All Species:
10.61
Human Site:
Y123
Identified Species:
19.44
UniProt:
Q15654
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q15654
NP_003293.2
476
50288
Y123
R
R
P
D
R
Q
A
Y
E
P
P
P
P
P
A
Chimpanzee
Pan troglodytes
XP_001159438
612
65827
K176
Q
P
P
L
T
A
T
K
K
S
T
L
K
P
Q
Rhesus Macaque
Macaca mulatta
XP_001106127
476
50267
Y123
R
R
P
E
R
Q
A
Y
E
P
L
P
P
P
A
Dog
Lupus familis
XP_536859
478
50671
Y123
R
R
S
D
R
Q
A
Y
E
P
P
Q
P
H
A
Cat
Felis silvestris
Mouse
Mus musculus
Q9Z1Y4
480
50915
F123
R
R
P
D
R
Q
A
F
E
A
P
P
P
H
A
Rat
Rattus norvegicus
Q5XI07
632
68242
S148
R
A
P
P
G
S
S
S
S
I
A
S
P
P
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506023
531
55801
V211
P
R
R
P
D
A
Q
V
Y
E
P
P
R
P
P
Chicken
Gallus gallus
Q5F464
604
65121
N170
H
K
R
M
I
I
P
N
Q
P
P
L
T
A
T
Frog
Xenopus laevis
A5H447
663
70707
A242
L
A
P
P
P
V
A
A
K
P
S
G
P
V
S
Zebra Danio
Brachydanio rerio
A8DZE6
648
70883
S177
Q
D
Q
S
K
H
T
S
P
R
S
S
I
S
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_396072
477
52619
C134
S
K
P
E
N
T
Y
C
N
I
S
S
A
H
N
Nematode Worm
Caenorhab. elegans
Q09476
413
46434
S103
P
P
V
Y
S
R
P
S
V
Q
S
L
L
S
Q
Sea Urchin
Strong. purpuratus
XP_798292
448
48550
H109
P
K
T
S
Q
R
H
H
E
L
S
N
A
R
G
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
44.1
98.3
89.3
N.A.
86.4
41.7
N.A.
58.5
43.3
30.4
28.7
N.A.
N.A.
36.6
21.4
39.9
Protein Similarity:
100
53.7
98.5
92.2
N.A.
90.2
51.2
N.A.
64.2
53.1
42.6
42.7
N.A.
N.A.
49
35.7
51.6
P-Site Identity:
100
13.3
86.6
80
N.A.
80
26.6
N.A.
26.6
13.3
26.6
0
N.A.
N.A.
6.6
0
6.6
P-Site Similarity:
100
26.6
93.3
80
N.A.
86.6
33.3
N.A.
26.6
26.6
40
20
N.A.
N.A.
20
6.6
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
16
0
0
0
16
39
8
0
8
8
0
16
8
31
% A
% Cys:
0
0
0
0
0
0
0
8
0
0
0
0
0
0
0
% C
% Asp:
0
8
0
24
8
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
16
0
0
0
0
39
8
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
8
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
8
0
0
0
0
0
0
8
0
0
8
% G
% His:
8
0
0
0
0
8
8
8
0
0
0
0
0
24
0
% H
% Ile:
0
0
0
0
8
8
0
0
0
16
0
0
8
0
0
% I
% Lys:
0
24
0
0
8
0
0
8
16
0
0
0
8
0
0
% K
% Leu:
8
0
0
8
0
0
0
0
0
8
8
24
8
0
0
% L
% Met:
0
0
0
8
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
8
0
0
8
8
0
0
8
0
0
8
% N
% Pro:
24
16
54
24
8
0
16
0
8
39
39
31
47
39
8
% P
% Gln:
16
0
8
0
8
31
8
0
8
8
0
8
0
0
16
% Q
% Arg:
39
39
16
0
31
16
0
0
0
8
0
0
8
8
0
% R
% Ser:
8
0
8
16
8
8
8
24
8
8
39
24
0
16
16
% S
% Thr:
0
0
8
0
8
8
16
0
0
0
8
0
8
0
8
% T
% Val:
0
0
8
0
0
8
0
8
8
0
0
0
0
8
8
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
8
0
0
8
24
8
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _